Mr. R. Kalirajan

R.KALIRAJAN (Alias) MANIVANNAN

Specialization: Pharmaceutical Chemistry

Email: rkalirajan@ymail.com
Phone: 0423-2443393(Ext: 223)
Fax: +91- 423- 2442937

Biography

Education
  • M. Pharm: Ist class from The TN Dr MGR Medical University, Chennai, TN 
  • Ph. D:  Pursuing from JSS University, Mysore
     
Work History
Present position
  • Asst. professor Department of Pharmaceutical Chemisty, JSS College of Pharmacy, Ooty, Tamilnadu, India.

Research Interests

  • Design, synthesis and biological evaluation of some novel hetrerocyclic compounds.  
     

Paper Publications

National

  1. Fluorimetric determination of Indol, V.Sankar, R.Kalirajan, F.Sweetlin, A.Krishnakumar and S.Raghuraman, Indian Drugs,38 (9),Sep-2001,490-491.
  2. Anti inflammatory  Activity of Elephantopus Scaper  in  Albino rats, V.Sankar, R.Kalirajan, F.Sweetlin Vivian Sales and S.Raghuraman Indian journal of Pharmaceutical sciences, November-2001, 523-525(Impact factor 0.455).
  3. Microwave Assisted Synthesis and Biological Evaluation of Pyrazole Derivatives of Benzimidazoles, R. Kalirajan*, Leela Rathore, S.Jubie, B.Gowramma, S.Gomathy, S.Sankar and K.Elango, Indian J.Pharm. Educ. Res., 44(4), Oct - Dec, 2010, 358-362. (Impact factor 0.163).
  4. Microwave assisted synthesis of some novel pyrazole substituted benzimidazoles and evaluation of their biological activities, R Kalirajan*, Leela Rathore, S Jubie, B Gowramma, S Gomathy & S Sankar, Indian Journal of Chemistry, Vol.50B, Dec,2011, 1794-1799. (Impact factor 0.562).

International

  1. Anti Nociceptive and Anti epileptic evaluation of N-Mannich bases of some substituted Benzotriazoles, V.Rajamanickam, P.Sivasubramaniyam, M.Palanivelu, R.Kalirajan, V.Sivakumar and K.Anandarajagopal,  International  Journal of Chemical Sciences, 4(4), 1048-1052, 2006.
  2. Synthesis and Biological Evaluation of Some Chalcone derivatives, R.Kalirajan, M.Palanivelu, V.Rajamanickam, G.Vinothapooshan and K.Anandarajagopal, International  Journal of Chemical Sciences, 5(1),73-80, 2007.
  3. Synthesis and biological evaluation of some theophylline derivatives. S.Jubie, R.Kalirajan, B.Gowramma, S.Sankar, K.Chandraprakash and B.Suresh. International Journal of Chemical Sciences, 5(5), 2007, 2223-2228.
  4. Synthesis and anesthetic activity of Some Mannich bases of P-Dimethylamino benzylidene acetanilide, R.Kalirajan, S.Jubie, B.Gowramma, B.Suresh, Asian Journal of Chemistry, 20(7), 5289-5292, 2008. (Impact factor 0.25)
  5. Simultaneous determination of Rabeprazole and Domperidone in Dosage forms by   RP-HPLC, R.Kalirajan, K.Anandarajagopal,   Seena mary Mathew, S.Jubie, B.Gowramma and B.Suresh,  Rasayan Journal of Chemistry, 1(2), 232-235, 2008.
  6. Comparative Evaluation of Theophylline microsphere prepared using various biodegradable polymers, G.Vinothapooshan, N.Jawahar, R.Kalirajan, S.Jubie, and B.Suresh, International  Journal of Chemical Sciences, 6(3), 1526-1534, 2008.
  7. synthesis and biological evaluation of some heterocyclic  derivatives of chalcones, R.Kalirajan, S.U.Sivakumar, S.Jubie,  B.Gowramma and B.Suresh,  International  Journal of Chem tech research- Vol.1,No.1, Jan-Mar 2009, 27-34.
  8. Synthesis and Antimicrobial Evaluation of some 2-Azetidinone derivatives  S.Jubie*, B.Gowramma, Nitin K.Muthal, R.Kalirajan, S.Gomathi and K.Elango,   International  Journal of Chem tech research- Vol.1,No.2, Apr-jun 2009, 153-157.
  9. Microwave induced Synthesis and Antimicrobial activity of  some Thiazine derivatives of 2-substituted Benzimidazole, R.Kalirajan, A.Justin, S.S.Dinesh narayanan, G.Venkatesh, S.Sankar, K.Elango, International journal of Pharma Research, Vol.2(2), Jan-jun 2009, 39-41.
  10. Synthesis and biological evaluation of Mannich bases of 2-substituted Benzimidazoles, R.Kalirajan, Chitra, S.Jubie and  B.Gowramma Asian Journal of Chemistry, Vol.21(7),2009, 5207-521.1(Impact factor 0.25)
  11. Synthesis of Quinazolone derivatives with Nitrogen mustards as possible Anticancer agents, B.Gowramma, R.Kalirajan, S.Jubie Asian Journal of Chemistry , Vol.21 (7), 2009, 5235-5240. (Impact factor 0.25)
  12. Synthesis, Anticancer activity of some 1-(Bis-N,N-(chloroethyl) aminoacetyl)-3,5-disubstituted 1,2-pyrazolines, B.Gowramma, S.Jubie, R.Kalirajan, S. Gomathy  and K.Elango. International Journal of PharmTech Research, Vol.1, No.2, 2009, 347-352.
  13. Design and Evaluation of  Sustained Release Hydrophilic Polymer Matrix Tablet of Glucosamine Sulphate, N.Jawahar, G.Vinothapooshan, Nagasamy venkadesh, R.Kalirajan, S.Jubie and T. Egappanath, Research Journal of Pharmacy and Technology, Vol. 2(3), July-sept., 2009, 463-465.
  14. Synthesis and biological evaluation of some 3 - (methoxy phenyl) - 2-aryl thiazolidin-4-one Derivatives, S. Jubie*, , B. Gowramma, K.M.Nitin, N.jawahar, R. Kalirajan, S. Gomathy, S.Sankar and k. Elango,  International Journal of Pharmaceutical Sciences, Vol.1 (1), 2009, 32-38.
  15. Antiepileptic and Antimicrobial Activities of Novel 1-(unsubstituted/ substituted) -3,5-dimethyl-1H- pyrazole Derivatives , K. Anandarajagopal*,    J. Anbu Jeba Sunilson, A. Illavarasu, N. Thangavelpandian, R. Kalirajan, International Journal of Chem.Tech.Research, Vol.2, No.1, 2010, 45-49.
  16. Synthesis and anti microbial activity of some novel ciprofloxacin analogues,  S. Jubie*, Pranabesh sikdar, R. Kalirajan, B. Gowramma, S. Gomathy, S.Sankar and k. Elango,  Journal of Pharmacy research,  Vol.3 (3), 2010, 511-513.
  17. Synthesis, Characterization and Antimicrobial Activity of Some Novel Oxazine Substituted Benzimidazoles, R. Kalirajan*, M. Azharudeen,  J. Hariharan, R. Yuvaraj, V. Mohan, S. Sankar and K Elango, Oct - Dec 2010, Vol. 1 (2), Inventi Impact Med Chem – online journal, Article ID - Inventi:mc/20/10.
  18. Synthesis and biological evaluation of some schiff bases of [4-(amino) -5- phenyl- 4h-1, 2, 4-triazole- 3- thiol],  Selvaraj jubie*, Pranabesh sikdar, Shanish antony, Rajagopal kalirajan, Byran gowramma, Subramanian gomathy and Kannan elango, Pak. J. Pharm. Sci., Vol.24, No.2, April 2011, 109-112. (Impact factor 0.825)
  19. Synthesis and Characterization of some Novel Quinoxaline-2, 3-Dione Derivatives: A Preliminary Investigation on their Activity Against a Human Epithelial Carcinoma Cell Line Selvaraj Jubie*, Rajamanickam Gayathri, Ammayappan Rajam Srividya, Rajagopal Kalirajan, Prabakaran Prabitha, Sundaram Sankar and Kannan Elango, Letters in Drug Design & Discovery, 2011, 8, 317-320. (Impact factor 0.805)
  20. Design, Synthesis and docking studies of novel ofloxacin analogues as antimicrobial agents, S.Jubie, P. prabitha, R.Rajeskumar, R.Kalirajan, R.Gayathri, S.Sankar and K.Elango, Medicinal Chemistry Research, July 2012, Volume 21, Issue 7, pp 1403-1410. (Impact factor 1.27 )
  21. New Benzimidazolo Indane-1, 3-Dione Derivatives: Synthesis and In-vitro Screening Against Helminthic Infections, S. Jubie*, R. Gayathri, A.R. Srividya, R. Kalirajan, S. Suresh, S. Sankar and K. Elango, International Journal of Drug Design and Discovery, Vol.1(2), April – June,  2011. 506-509.
  22. Synthesis, Characterization and antimicrobial evaluation of some novel 1,3,4-Thiadiazole derivatives, Byran Gowramma, Subramani Gomathy and Rajagopal Kalirajan, International journal of Pharmaceutical Sciences and Research, 2011, 2(6), 1476-1479.
  23. Design, Synthesis and Docking Studies of a Novel Ciprofloxacin Analogue as an Antimicrobial AGENT, S. Jubie, R. Kalirajan, and Pavankumar Yadav E-Journal of Chemistry, Volume 9 (2012), Issue 2, Pages 980-987. (Impact factor 0.716)
  24. Docking studies, Synthesis, Characterization and Evaluation of their Antioxidant and cytotoxic activities of some Novel Isoxazole substituted 9-anilinoacridine derivatives. R.Kalirajan*, M.H.Mohammed rafick, S.Sankar and S.Jubie, The Scientific World Journal, - Volume 2012, Article ID 165258, 6 pages, doi:10.1100/2012/165258 (Impact factor 1.5)
  25. Synthesis and Neuropharmacological Evaluation of Some Novel Quinoxaline 2, 3-Dione Derivatives," by Selvaraj Jubie, Rajamanickam Gayathri and Rajagopal Kalirajan, The Scientific World Journal, Volume 2012, Article ID 718023, 8 pages doi:10.1100/2012/718023 - (Impact factor 1.5).
  26. Synthesis, antidepressant and antimicrobial activities of some novel stearicacid analogues, Selvaraj Jubie, Patil Nilesh Ramesh, Palanichamy Dhanabal, Rajagopal Kalirajan, Nithyanantham Muruganantham, Anthoniswamy Shanish Antony, European Journal of Medicinal Chemistry,  Vol. 54, Aug 2012 931-935 (Impact factor 3.5)
  27. Synthesis of some novel pyrazole substituted 9-anilino acridine derivatives and evaluation for their antioxidant and cytotoxic activities, R.Kalirajan*, V.Muralidharan, S.Jubie, B.Gowramma, S.Gomathy, S.Sankar and K.Elango, Journal of Heterocyclic chemistry, Vol.49, July 2012, 748-754. (Impact factor 1.22).
  28. Docking studies, synthesis, characterization of some novel oxazine substituted 9-anilinoacridine derivatives and evaluation for their anti oxidant and anticancer activities as topo isomerase ii inhibitors, R.Kalirajan*, Vivek kulshrestha, S.Sankar and S.Jubie, European Journal of Medicinal Chemistry, Vol. 56, Oct 2012 217-224. (Impact factor 3.5).

PAPER PRESENTATIONS

  1. Synthesis, Characterization and Biological Evaluation of some novel azo      Derivatives, 57th IPC, Hyderabad, Page-189., 2005
  2. Anti-Nociceptive evaluation of novel newly synthesized 1-[2-(1H-Tetrazol-5yl)ethyl ] – 1H – Benzo [d] 1,2,3-triazoles. Second international conference, JSS College of Pharmacy, Ooty, DD-93, Page-184, Feb-2007.
  3. Multiple Sequence alignment using an Exhaustive and Greedy  Algorithm, Second international conference, JSS College of Pharmacy, Ooty, PP-41, Page-294, Feb-2007.
  4. The probability distribution for A Random match between an Experimental- Theoritical Spectral pair in Tandem Mass Spectrometry- Proteomics, Second international conference, JSS College of Pharmacy, Ooty, PP-42, Page-295, Feb-2007.
  5. Post- Exposure Prophylaxis for SIV Revisited : Animal model for HIV Prevention, Second international conference, JSS College of Pharmacy, Ooty, PP-43, Page-295, Feb-2007.
  6. Synthesis and evaluation of antimitotic activity of 3-oxo indoline derivatives of 2-phenyl quinazoline, R Kalirajan, Egappanath. S Sankar, P Dhamodaran, 60th IPC, Delhi, MC-73, December, 2008, P- 202.
  7. Microwave induced synthesis and antimicrobial activity of thiazine derivatives of benzimidazole, R.Kalirajan, Leela rathore, S.Jubie and B.Gowramma, 60th IPC, Delhi, MC-158, December, 2008, P- 224.
  8. Synthesis and biological  evaluation of some indane1,3 dione derivatives, S Jubie. pranabesh sikdar, B Gowramma, R Kalirajan, 60th IPC, Delhi, MC-84, December, 2008, P- 205.
  9. Synthesis and biological evaluation of some derivatives of4-thiazolldinones and  2-azetidinones, S. Jubie, Nitin K Muthal. B Gowramma, R Kalirajan, 60th IPC, Delhi, MC-85, December, 2008, P- 205.
  10. Microwave induced synthesis and antimicrobial activity of Oxazine derivatives of benzimidazole, R.Kalirajan, M.H. Mohammed rafick, S.Sankar and K.Elango, 61st IPC, Ahmedabad, B-229, December, 12, 2009, P- 265.
  11. Microwave Induced Synthesis and Cytotoxic activity of some Novel Pyrazole substituted 9-Anilino Acridine derivatives, R.Kalirajan, M.H. Mohammed rafick, V.Muralidaran and S.Sankar, 62nd IPC, Manipal, B-9, December, 17, 2010, P-.
  12. Synthesis, Characterization and evaluation of their antioxidant activity of some Novel Pyrazole substituted Acridine derivatives, R.Kalirajan, Ravi kishore,  V.Muralidaran and S.Sankar, 62nd IPC, Manipal, B-14, December, 17, 2010, P-.
  13. Synthesis, Characterization and evaluation of anti microbial activity of some Novel Chalcone derivatives of 9-Anilino Acridine R.Kalirajan, Priyasingh, V.Muralidaran and S.Sankar, 62nd IPC, Manipal, B-10, December, 17, 2010, P-.
  14. Microwave Induced Synthesis and Antimicrobial activity of some Novel Isoxazole substituted 9-Anilino Acridine derivatives. R.Kalirajan, M.H.Mohammed rafick and S.Sankar, Indo-US Bilateral symposium on Frontiers in Medicinal Chemistry and Drug Discovery, JSS University, Mysore, 21-23, April 2011.
  15. Microwave assisted Synthesis of some Novel chalcone substituted 9-Anilino Acridine derivatives and evaluation of Larvicidal activity, R.Kalirajan, Vivek Kulshrestha and S.Sankar, Indo-US Bilateral symposium on Frontiers in Medicinal Chemistry and Drug Discovery, JSS University, Mysore, 21-23, April 2011.
  16. Microwave assisted Synthesis, Characterization and Evaluation of Their Larvicidal activity of some Novel chalcone substituted Acridine derivatives, R.Kalirajan, Tanuja pathak, M.H.Mohammed rafick and S.Sankar, 63rd IPC,  16-18 December 2011, Bengaluru, B-364.
  17. Microwave Induced Synthesis and Antioxidant activity of some Novel Isoxazole substituted 9-Anilino Acridine derivatives, R.Kalirajan, Vivek Kulshrestha, M.H.Mohammed rafick and S.Sankar, 63rd IPC,  16-18 December 2011, Bengaluru, B-361.

BOOK Published
Title -"MW synthesis and biological activities of benzimidazole with pyrazoles ",
Author- Kalirajan Rajagopal, ISBN -978-3-659-23085-1,
LAP LAMBERT Academic Press, Germany

Professional Activities
    Life membership of Indian Pharmaceutical Association (TN/NIL/LM/ 050  )
    Registered Pharmacist of Tamilnadu Pharmacy Council (3482A1)