Biotechnology

Department of Biotechnology

Vision :
The Department of Pharmaceutical Biotechnology keeps its vision to be a nodal centre for Animal Tissue culture technology development for Biopharmaceutical Products by the Year 2015.

Mission :
The Department of Pharmaceutical Biotechnology has the mission to equip the pharmacy students with adequate theoretical and practical knowledge in Industrial microbiology, Bioprocess technology, Animal Tissue Culture and other modern molecular biotechnology techniques like Cloning, Sequencing,Hybridoma etc. to make them employable in the Pharma Biotech Companies.

Faculty Details

S.No. Name Qualification Designation
01 Dr.M.K.Samanta M.Pharm,PhD Head & Professor
02 Mrs.A.R.Srividhya M.Pharm Asst.Professor
03 Mr.R.Rajeshkumar M.Pharm Lecturer

Programmes organised (QIP/SDP/Workshop/Seminar)

Sl. No. Title of the programme Sponsoring agency Date (s) Outcome

NIL

 NIL NIL NIL NIL

Broad research areas

1. Invitro Cell Culture based antiviral and anticancer studies

2. Studies on secondary metabolites from soil samples

3. DNA Fingerprinting

4. Monoclonal antibody based drug delivery system

5. Nanobiotechnology

Top 20 Scientific Publications (International and National)

International:-04 National:-06

Sl. No.

Title of the paper

Authors

Journal, Vol, Ed, Page No.

Name of the Publisher

Impact Factor

01

Design and evaluation of chitosan nanoparticles as novel drug carrier for the delivery of rivastigmine to treat Alzheimer’s disease.

Malay K,Samanta,Madaswamy S.Muthu,and Ganesan

Barnabas Wilson, Vinothapooshan

Therapeutic Delivery

(2011)2 (5),509-609

Future Science Group

1.424

02

Consecutive Assessment of Taxanes by Prominence UFLC from Biological Samples

Manjunatha Narayanappa,Anil Dubala,Rizwanbasha Khatwal,Jayasankar Kosaraju,Kalpesh Patel,Dinesh Sindhe,Malay K.Samanta

Journal of pharmacy Research

4(11)3978-3981 2011

JPR Solution

1.09

03

Establishment of Pharmacokinetic parameters for the herbal drug containing forskolin

Journal of Pharmacy research

4:2303-2306,

2011

Duja

1.09

04

Bioanalytical method development and validation of sitagliptin phosphate by RP-HPLC and its application to pharmacokinetic study.

Anil Dubala,Rizwanbasha Khatwal,Jaya Sankar Kosarju,Venkat Meda,Malay K.Samanta

International Journal of Pharmacy and Pharmaceutical Science

4(2) 2012.

Academic Sciences

0.38

01

Isolation Quantification and Purity Estimation of DNA from Various Sources

Ammayappan Rajam,Srividya,Hardik Taakore,Devkant Tyagi,Pritam Majumdar,James,Vishmu Varthan V.J.,Patel Jenish H,and Lad Krunal V

Bulletin of Pharmaceutical Research, April 2011:1(1),126-134

­

Association of Pharmacy Professional

online

02

Probiotic: a rational approach to use Probiotic as medicine

Srividya A.R.

International Journal of Pharmaceutical Research

1 (1); 126-134.

April-June-2011

Association Pharmaceutical Education and Research

Online

03

Design,Synthesis and docking studies of novel ofloxacin analogues as antimicrobial agents,

S.Jubie,P.Prabitha,R.Rajeshkumar,R.Kalirajan,R.Gayathri,

S.Sankar,k.Elango

Medicinal Chemistry Research

3,1-8

April-2011

Springer

Journals

1.058

04

Antioxidant and Antidiabetic ctivity of Curcuma Aromatica,

Ammayappan Rajam Srividya,Palanisamy Dhanabal,Parthkumar Bavadia,Vaithiyalingam Jagannathan Vishnuvarthan,Muthureddy Natarajan Sathish Kumar

IJRAP 3(3) May-June2012

Ayurveda college,Kottakkal

Online

05

Phytopreventive Antihyperlipidemic Activity of Curcuma Zedoaria,

A.R.SriVidya,S.P.Dhanabal,Ajit Kumar Yadav,M.N.Sathish Kumar,V.J.Vishnuvarthan

Bulletin of Pharmaceutical Research, 2012 ;2(1);22-5

Association of Pharmacy Professionals

Online

06

Determination and Estimation of Pharmacokinetic Profile

of Caffeine in Form of Extract of Green Tea Leaves and its

Analogy with Synthetic Form

Sangeetha Shanmugasundaram, N. Manjunatha*, R. Vijayan, R. B. Khatwal And M. K. Samanta

Indian Journal of Pharmaceutical Sciences

November - December 2011

Page No.55-61

--------

------

Patents Filed/Granted:-NILResearch Papers Presented

Sl. No.

Title of presentation

Presenting Author

Name of the Seminar/Conferences/Workshops

Organised by and date (s)

 

01

Optimization of Parameters for production of Fungal lipases using agro waste

Rachana.K

GITAM Institute of Pharmacy,GITAM University,Visakhapatnam

29th 7& 30th

July 2011

02

In vitro Brain Targeting and Pharmacodynamic characterization of PBCA and PLGA Nanoparticles Containing Tacrine for the Treatment of Alzheimer’s Disease

Development, In Vivo and in Vivo characterization of PLA

Nanopartion and Containing Tamoxifen for cancer Therapy.

Mr.Rizwan Basha Khatwal

Mr.Rizwan Basha Khatwal

2nd Nano Today Elsevier

Conference -2011 Hawaii,

USA

2nd Nano Today Elsevier

Conference -2011 Hawaii,

USA.

12 -15 Dec,2011

12 -15 Dec,2011

03

In Vitro and in vivo viral Inhibitory Activity of Hypericum species against Newcastle Disease virus

Mr.Ashish wadhwani

Kuala Lumpur, Malaysia

Asian Federation for pharmaceutical Sciences,

Dated.9-12 Dec,2011

04

AntiProliferation and Induction of Apoptosis by Hydro alcoholic extract of Cassia alata Linn

Mr. Viral Patel

An American Association for International new Horizon in Cancer Research Gurgaon,Delhi

Dated 13-16 December, 2011.

05

Optimization of the parameters for production of fungal lipase by SSF fermentation using the selected agro waste

Rachana Katta

IPC Bangalore,

Dated.16-18 Dec,2011

Research projects from various funding agencies

Research Grants received

Sl. No.

Project Title

Principal Investigator

Funding Agency

Amount

01

Travel grant applied to present the poster at 2nd Nano Today, Hawaii conference entitled “In vitro Brain Targeting and Pharmacodymamic Characterization of PBCA and PLGA nanoparticles containing Tacrine for the treatment of Alzhiemer’s disease

Mr. Rizwan Basha

ICMR-Travel Grant CSIR-Travel Grant

92,135/-

02

In Vitro and in vivo viral in inhibitory activity of Hypericum species against New castle disease Virus

Mr.Ashish Wadhani

JSS University IPA Central Branch Mumbai.

Travel Grant

64,000/-

03

Anti-Proliferation and Indication of Apoptosis by HA extract of Cassia alata

Mr.Patel Viral

IPA Nilgiris –Travel Grant

5300/-

04

Nano-Immuno-Drug Conjugates: A Target Specific Therapy for the Regeneration of Pancreatic Beta Cells in Diabetic Insulitis Conditions

Dr.M.K.Samanta

DBT-Nano Biotechnology

Concept Proposal

Submitted

05

Nano-Immuno-Drug Conjugated Delivery System for the Regeneration of Pancreatic Beta Cells in Diabetic Apoptotic Conditions

Dr.M.K.Samanta

DBT-NE

69.284 lakhs

Submitted

06

Botanical Drug Development for Unique Antiviral Efficacy Against Both

Enveloped and Non Enveloped Viruses.

Dr.M.K.Samanta

DBT-Nano Biotechnology

Concept Proposal

Submitted

07

Neuroprotection by Selective Allosteric Potentiators of MI Muscarnic Receptor to Restore Reversal Learning Management in Alzheimers Disease

Dr.M.K.Samanta

DST - Concept Proposal

60,00,000/-

Submitted

08

Travel grant to attend 2012 AAPS Meeting and Symposium at Chicago, October 14 to 18th 2012

Dr.M.K.Samanta

ICMR-Travel grant

83750/-

Received

Ongoing Projects

Sl. No.

Project Title

Principal Investigator

Funding Agency

Amount

NIL

NIL

NIL

NIL

NIL

Students fellowships Received

Sl. No.

Project Title

Name of the scholar

Agency

Fellowships

01.

Investigation of anticancer activity of selected medicinal plants.

Mr.Viral Patel under Dr.P.Vijayan

CSIR New Delhi

2,36,000/-

Honours & achievements

1. CSIR-Fellowship award by Mr.Ashish D.W.& Viral Patel, PhD Scholars

2. One Gold Medal Under JSS University,Mysore

3. Dr. M.K.Samanta selected as the Guest Editor, Special Issue Edition, Journal of Drug Delivery, Hindawi Publishing Corporation, USA,

4. Ammayappan rajan Srividya have been selected by the American biographic institute to be a reciepient of its medical science award of excellence 2011 for the professional contribution to the well being of the society.

5. Mrs. Ammayappan Rajam Srividya has been seleced for the Institute's "Man of the year in Medicine & Healthcare" designation for 2011 by the American Biographical Institute, Inc, North California, USA

6. Mrs. Ammayappan Rajam Srividya has been noted as an eminent Professional in health profession and nominated for the Award "Top 100 Health Professional 2011" as well as nominated as a member of International Biographical Centre, Cambridge, England7. Ammayappan Rajams Srividhya have been chosen for a distinct honor "Great Minds of the 21st century". by the Governing Board of Editors of American Biographical Institute, Inc, Host of the wored  Forum, San Francisco, California 2011.

8. Mr.Ashish Wadhwani Research Scholar received the honorary membership for Asian Federation of Pharmaceutical Sciences,Japan and also accepted for a poster presentation In AFPS Conference-2011 at Malaysia

9. Dr. M.K. Samanta chaired one scientific session at 63rd IPC, Bangalore, 16-18 December, 2011

Guest Lectures delivered

Sl. No.

Title of presentation

Faculty

Name of the Seminar/Conferences/Workshops

Organised by and date (s)

 

01

Physical Exposure and Human Health

Dr.M.K.Samanta

Barefoot College, Coonoor

Rotary Club of Niligirs,Coonoor

02

The role of exercise in keepngs people healthy

Mrs.A.R.Srividhya

Mr.Ashish Wadhwani

Mr.Viral Patel

Lawrence School,Coonoor,The Nilgiris

March 27th 2012

Invited Lectures Organised

Sl. No.

Name and address of the Guest speaker

Title of presentation

Date

01

Mr.Annappa.S

BD Bioscience, Bangalore

Application of Biotechnology /Microbiology in Industries

19th September 2011

Industrial visit of staff / students

1. II.M.Pharm Students deputed for training at Workhardt Ltd,Aurangsbad from July 2011 for a month Mr.Dinesh & Mr.Pusparaj

Training and Placement

1. Giri Prashant Dattatraya,Biocon Industrial,Bangalore

2. T. Mahesh, Biocon Industrial,Bangalore

3. Mr.Dinesh Patidar-Indore Pharmaceuticals,Indore

4 . Monica Mishra- Wookhard Ltd, Baddy

Major Instruments/Equipments available

S.No

Name of Instruments/Equipments

01.

Autoclave 2KW

02.

BOD Incubatore

03.

BioMate-5

04.

Centrifuge Cooling

05.

Centrifuge Bench

06.

Co2 Incubatore

07.

DNA Sequencer

08.

Electrophoretie System

09.

Elisa reader

10.

Gel Documentation System

11.

Fermenter System

12.

Hot air oven

13.

HPLC

14.

Incubatore Shaker

15.

Laminar air flow systems

16.

Millipore filter system

17.

Orbital water bath shaker

18.

PCR Personal

19.

Sonicator